NMN has been able to suppress age-associated weight gain, enhance energy metabolism and physical activity, improve insulin sensitivity, improve eye function, improve mitochondrial metabolism and prevent age-linked changes in gene expression. This nucleotide acts as a precursor to NAD+. Supplementation has been shown to increase levels of NAD+ in the body, which has a variety of potential health benefits. NAD+ plays an important role in energy metabolism, and its levels decline with age. This may contribute to the age-related decline in metabolism and physical function.